Motif ID: STAT5{A,B}.p2

Z-value: 1.458


Transcription factors associated with STAT5{A,B}.p2:

Gene SymbolEntrez IDGene Name
STAT5A 6776 signal transducer and activator of transcription 5A
STAT5B 6777 signal transducer and activator of transcription 5B

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
STAT5Bchr17_-_37681917-0.665.2e-03Click!
STAT5Achr17_+_37693090-0.591.7e-02Click!


Activity profile for motif STAT5{A,B}.p2.

activity profile for motif STAT5{A,B}.p2


Sorted Z-values histogram for motif STAT5{A,B}.p2

Sorted Z-values for motif STAT5{A,B}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of STAT5{A,B}.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr19_+_39860398 3.758 NM_001012320
NM_018443
ZNF302

zinc finger protein 302

chr19_-_39859997 3.223


chr5_+_145297490 2.626 SH3RF2
SH3 domain containing ring finger 2
chr19_+_49180171 2.589 NM_003445
NM_198089
ZNF155

zinc finger protein 155

chr19_+_49248003 2.199 NM_013361
ZNF223
zinc finger protein 223
chr19_+_61798434 1.992 NM_021216
ZNF71
zinc finger protein 71
chr19_+_42099073 1.923 NM_198539
ZNF568
zinc finger protein 568
chr19_-_41849558 1.874 NM_153257
ZNF461
zinc finger protein 461
chr4_+_86615275 1.764 NM_001025616
ARHGAP24
Rho GTPase activating protein 24
chr19_-_42098758 1.707 NM_001171979
ZNF829
zinc finger protein 829
chr1_+_148137778 1.421 NM_016074
BOLA1
bolA homolog 1 (E. coli)
chr19_+_58733144 1.314 NM_001079906
ZNF331
zinc finger protein 331
chr14_+_23700261 1.259 NM_006084
IRF9
interferon regulatory factor 9
chr19_+_42033106 1.207 NM_003419
ZNF345
zinc finger protein 345
chr19_+_42033564 1.099 ZNF345
zinc finger protein 345
chr6_-_46728188 1.082 NM_016593
CYP39A1
cytochrome P450, family 39, subfamily A, polypeptide 1
chr15_+_39853982 1.078 MAPKBP1
mitogen-activated protein kinase binding protein 1
chr11_-_33678861 1.060 NM_001166692
C11orf91
chromosome 11 open reading frame 91
chr7_+_89870707 1.013 CLDN12
claudin 12
chr19_-_42098919 0.975 NM_001037232
ZNF829
zinc finger protein 829

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 15 of 15 entries
enrichment   p-value GO term description
2.04 1.08e-06 GO:0006355 regulation of transcription, DNA-dependent
1.97 5.84e-06 GO:0051252 regulation of RNA metabolic process
1.92 8.51e-06 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.87 2.71e-05 GO:0010556 regulation of macromolecule biosynthetic process
1.86 2.07e-05 GO:0010468 regulation of gene expression
1.80 6.34e-05 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.75 2.31e-04 GO:0051171 regulation of nitrogen compound metabolic process
1.74 5.76e-04 GO:0031326 regulation of cellular biosynthetic process
1.72 9.00e-04 GO:0009889 regulation of biosynthetic process
1.63 6.74e-04 GO:0060255 regulation of macromolecule metabolic process
1.58 1.91e-03 GO:0031323 regulation of cellular metabolic process
1.58 1.94e-03 GO:0080090 regulation of primary metabolic process
1.52 4.11e-03 GO:0019222 regulation of metabolic process
1.30 3.83e-02 GO:0050794 regulation of cellular process
1.29 9.60e-03 GO:0065007 biological regulation

Gene overrepresentation in compartment category:

Showing 1 to 9 of 9 entries
enrichment   p-value GO term description
1.50 1.29e-06 GO:0005634 nucleus
1.37 8.86e-09 GO:0043231 intracellular membrane-bounded organelle
1.37 1.00e-08 GO:0043227 membrane-bounded organelle
1.36 9.99e-11 GO:0043229 intracellular organelle
1.36 1.27e-10 GO:0043226 organelle
1.23 1.26e-06 GO:0044424 intracellular part
1.22 4.12e-06 GO:0005622 intracellular
1.08 4.05e-02 GO:0044464 cell part
1.08 4.09e-02 GO:0005623 cell

Gene overrepresentation in function category:

Showing 1 to 7 of 7 entries
enrichment   p-value GO term description
2.06 2.47e-07 GO:0008270 zinc ion binding
2.05 1.32e-08 GO:0003677 DNA binding
2.00 8.63e-08 GO:0046914 transition metal ion binding
1.63 8.42e-05 GO:0003676 nucleic acid binding
1.54 2.53e-04 GO:0046872 metal ion binding
1.52 4.36e-04 GO:0043169 cation binding
1.52 4.91e-04 GO:0043167 ion binding